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 Biomedical researchers create artificial human bone marrow in a test tube

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Date posted: 23/12/2008

Artificial bone marrow that can continuously make red and white blood cells has been created in a University of Michigan lab.

The substance grows on a 3-D scaffold that mimics the tissues supporting bone marrow in the body. It can replicate blood stem cells and produce B cells, the key immune cells producing antibodies that are important to fighting many diseases.

Nicholas Kotov, a professor in the U-M departments of Chemical Engineering; Materials Science and Engineering; and Biomedical Engineering said. "The scaffold for this work had to be designed from scratch closely mimicking real bone marrow because there are no suitable commercially products.

"Certain stem cells that are essential for immunity and blood production are able to grow, divide and differentiate efficiently in these scaffolds due to the close similarity of the pores in the scaffold and the pores in actual bone marrow."

See the full Story via external site: www.eurekalert.org



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