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 InDevR's FluChip detects, distinguishes swine-origin H1N1 from human influenza viruses

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Date posted: 05/05/2009

InDevR, a small biotech company in Boulder, CO, and the Influenza Division of the Centers for Disease Control and Prevention (CDC) in Atlanta confirmed today that the M gene version of InDevR's FluChip can detect swine-origin H1N1 influenza A viruses and clearly distinguish them from seasonal influenza viruses (A/H1N1 and A/H3N2) as well as the deadly avian A/H5N1 virus.

The FluChip was invented by a joint team of scientists at the University of Colorado at Boulder and the Centers for Disease Control and Prevention in an NIAID-supported effort led by then-Professor Kathy Rowlen, CEO of InDevR. InDevR recently licensed the intellectual property from the University of Colorado and CDC.

The CDC provided InDevR scientists with non-infectious genetic material from swine-origin influenza viruses earlier this week. The FluChip performance was evaluated with several of these samples in a side-by-side comparison with seasonal human influenza viruses. "The FluChip assay detected all of the 6 swine-origin H1N1 viruses tested, and the resulting pattern, or signature, on the microarray was dramatically different than the signature for seasonal A/H1N1 and A/H3N2 viruses. Interestingly, the signature of the swine H1N1 virus indicated an avian component within the M-gene, which is consistent with its reported Eurasian lineage, said Dr. Erica Dawson, the Lead Scientist on the project at InDevR and co-inventor of the FluChip technology.

See the full Story via external site: www.physorg.com



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