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 "Memory Code" Discovered in Brain

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Date posted: 11/04/2005

In a concerted effort to understand exactly how memories are formed and stored, the activity of hundreds of mouse brain cells have been simultaneously recorded using a specially developed 96-channel electrode array neuroprosthetic.

Joe Tsien of Boston and Princeton universities and colleagues simultaneously recorded the electrical activity of up to 260 individual neurones in the mouse hippocampus, where memories of places and events are formed.

It was discovered that specific signals, which the researchers call "neural cliques" were sent, just before activity in parts of the hippocampus changed, exactly the same as control signals in computers. Even more importantly, these activation patterns were identical, in the brains of different mice, suggesting that the codes for memory formation are universal.

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